【摘要】 目的：體檢普篩腦卒中高危人群，研究血脂異常、高血壓患者的腦血管血液動(dòng)力學(xué)變化特征和血脂異常、高血壓分別與腦血管血液動(dòng)力學(xué)檢測(cè)（CVHD）異常值之間關(guān)系，了解本地區(qū)腦卒中高危人群的風(fēng)險(xiǎn)因素。方法：對(duì)2015年7月-2017年6月間東莞市區(qū)及其鎮(zhèn)區(qū)來本院體檢的45～79歲共
　　3 931例做CVHD，同時(shí)入選人群均進(jìn)行測(cè)血壓、體質(zhì)指數(shù)、血脂四項(xiàng)等項(xiàng)目檢查。觀察血脂異常、高血壓人群的腦血管血液動(dòng)力學(xué)參數(shù)（CVHI）變化，比較CVHD正常（積分值>75分）人群和CVHD異常病例（積分值≤75分）的血脂異常、高血壓檢出率（暴露率）。結(jié)果：CVHD評(píng)估積分值正常組有3 748例，占95.3%；CVHD評(píng)估積分值異常組有183例，占4.7%。其中CVHD評(píng)估積分值正常組的高血壓、低密度脂蛋白膽固醇（LDL-C）異常檢出率（暴露率）分別是19.8%，18.1%；CVHD評(píng)估積分值異常組的高血壓、低密度脂蛋白膽固醇異常檢出率（暴露率）分別是71.0%，73.2%。兩組間高血壓、LDL-C異常暴露率比較差異均有統(tǒng)計(jì)學(xué)意義（P<0.01）。結(jié)論：本研究證實(shí)，該體檢人群中CVHD積分值異常病例的高血壓、LDL-C異常風(fēng)險(xiǎn)因素暴露率明顯高于CVHD積分值正常組，說明CVHD異常積分值與高血壓、血脂異常等風(fēng)險(xiǎn)因素明顯相關(guān)，運(yùn)用CVHD有利于評(píng)估早期腦卒中的高風(fēng)險(xiǎn)體檢人群，促進(jìn)其早期積極預(yù)防和干預(yù)。
　　【關(guān)鍵詞】 腦血管血液動(dòng)力學(xué)； 腦卒中； 普篩； 異常值； 危險(xiǎn)因素
　　Relationship between Abnormal Integral Value of Cerebrovascular Hemodynamic Detection with Dyslipidemia and Hypertension/WANG Jihua，XING Li，SONG Fangwen，et al.//Medical Innovation of China，2018，15（07）：024-027
　　【Abstract】 Objective：To study the characteristics of cerebral vascular hemodynamics in patients with dyslipidemia and hypertension， to study the relationship between dyslipidemia，hypertension and cerebral vascular hemodynamic detection （CVHD） by medical screening，to understand the risk factors of people at high risk of stroke in the region of the group.Method：A total of 3 931 cases of 45-79 years old who received physical examination in Dongguan urban area and their townships from July 2015 to June 2017 were selected for CVHD.Meanwhile，all the candidates were tested for blood pressure，body mass index and blood lipid four items.Changes in hemodynamic parameters （CVHI） of cerebral blood vessels in people with hyperlipidemia and hypertension were observed.The detection rate of dyslipidemia and hypertension （exposure） of normal CVHD （score>75 points） and CVHD abnormal cases （abnormal crowd integral value≤75 points） were compared.Result：CVHD had evaluated the normal group with 3 748 cases，accounting for 95.3%.CVHD had evaluated the abnormal components in 183 cases， accounting for 4.7%.Among them， hypertension ， low density lipoprotein cholesterol （LDL-C） abnormal detection rate （exposure rate） were 19.8% and 18.1% respectively in the normal group；the abnormal detection rate （exposure rate） of hypertension and low density lipoprotein cholesterol were 71.0% and 73.2% in the abnormal group. There were statistically significant differences between the two groups in hypertension and LDL-C exposure（P<0.01）.Conclusion：This study confirms that the CVHD abnormal cases have high risk factors of hypertension and dyslipidemia ，their hypertension and LDL-C abnormal exposure rate are significantly higher than the CVHD normal group， indicating that CVHD abnormal integral value is significantly associated with hypertension， dyslipidemia and other risk factors.The use of CVHD is helpful for assessing the early detection of high risk patients of stroke and assisting the early prevention and intervention.

相關(guān)熱詞搜索：異常 腦血管 高血壓 動(dòng)力學(xué) 血脂